Anti-KLK7 Polyclonal Antibody
品牌：solarbio | 货号：K004044P
| 英文名称 | Anti-KLK7 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PRSS6;SCCE;hK7 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 28kDa |
| Gene ID | 5650 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human KLK7 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human KLK7 |
| Subcellular Locations | Secreted |
| Swiss Prot | P49862 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. |