Anti-OCLN Polyclonal Antibody
品牌：solarbio | 货号：K003448P
| 英文名称 | Anti-OCLN Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BLCPMG;PPP1R115 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:1000-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 59kDa |
| Gene ID | 100506658 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human OCLN |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human OCLN |
| Subcellular Locations | Cell junction Membrane Multi-pass membrane protein tight junction |
| Swiss Prot | Q16625 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. |