Anti-DSG1 Polyclonal Antibody
品牌：solarbio | 货号：K006060P
| 英文名称 | Anti-DSG1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CDHF4;DG1;DSG;EPKHE;EPKHIA;PPKS1;SPPK1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 114kDa |
| Gene ID | 1828 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human DSG1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human DSG1 |
| Subcellular Locations | Cell junction Cell membrane Single-pass type I membrane protein desmosome |
| Swiss Prot | Q02413 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. |