Anti-GTPBP4 Polyclonal Antibody
品牌：solarbio | 货号：K003821P
| 英文名称 | Anti-GTPBP4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CRFG;NGB;NOG1 |
| 应用 | WB |
| 稀释比例 | WB 1:1000-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 74kDa |
| Gene ID | 23560 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human GTPBP4 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human GTPBP4 |
| Subcellular Locations | Nucleus nucleolus |
| Swiss Prot | Q9BZE4 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. ‘Active’ in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. |