Anti-SPHK2 Polyclonal Antibody
品牌:solarbio | 货号:K006941P
英文名称 |
Anti-SPHK2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
SK 2;SK-2;SPK 2;SPK-2 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:25-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
69kDa |
Gene ID |
56848 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human SPHK2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human SPHK2 |
Subcellular Locations |
Cytoplasm membrane |
Swiss Prot |
Q9NRA0 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.? |