Anti-IRF4 Polyclonal Antibody
品牌：solarbio | 货号：K007743P
| 英文名称 | Anti-IRF4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MUM1;LSIRF;NF-EM5 |
| 应用 | WB |
| 稀释比例 | WB 1:200-1000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 52kDa |
| Gene ID | 3662 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human IRF4 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human IRF4 |
| Swiss Prot | Q15306 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. |