Anti-SMARCE1 Polyclonal Antibody
品牌:solarbio | 货号:K003940P
| 英文名称 | Anti-SMARCE1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BAF57;CSS5 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 47kDa |
| Gene ID | 6605 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SMARCE1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SMARCE1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q969G3 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. |