Anti-TBX1 Polyclonal Antibody
品牌：solarbio | 货号：K007865P
| 英文名称 | Anti-TBX1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DGS;TGA;VCF;CAFS;CTHM;DGCR;DORV;VCFS;TBX1C;CATCH22 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:25-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 43kDa |
| Gene ID | 6899 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human TBX1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human TBX1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | O43435 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. |