Anti-Phospho-IκBα-S32/36 Polyclonal Antibody
品牌：solarbio | 货号：K006254P
| 英文名称 | Anti-Phospho-IκBα-S32/36 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | IKBA;MAD-3;NFKBI |
| 应用 | WB |
| 稀释比例 | WB 1:500-1000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 36kDa |
| Gene ID | 4792 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A phospho specific peptide corresponding to residues surrounding S32/36 of human IκBα |
| 性状 | 液体 |
| Public Immunogen Range | A phospho specific peptide corresponding to residues surrounding S32/36 of human IκBα |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P25963 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. |