Anti-RGS10 Polyclonal Antibody
品牌:solarbio | 货号:K006124P
英文名称 |
Anti-RGS10 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
RGS10 |
应用 |
WB |
稀释比例 |
WB 1:200-500. |
交叉反应 |
Human Rat |
蛋白分子量 |
20kDa |
Gene ID |
6001 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human RGS10 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human RGS10 |
Subcellular Locations |
Cytosol Nucleus |
Swiss Prot |
O43665 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. |