Anti-RGS10 Polyclonal Antibody
品牌:solarbio | 货号:K006124P
| 英文名称 | Anti-RGS10 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | RGS10 |
| 应用 | WB |
| 稀释比例 | WB 1:200-500. |
| 交叉反应 | Human Rat |
| 蛋白分子量 | 20kDa |
| Gene ID | 6001 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RGS10 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RGS10 |
| Subcellular Locations | Cytosol Nucleus |
| Swiss Prot | O43665 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. |