Anti-BPGM Polyclonal Antibody
品牌：solarbio | 货号：K005525P
| 英文名称 | Anti-BPGM Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DPGM |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 30kDa |
| Gene ID | 669 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human BPGM |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human BPGM |
| Subcellular Locations | Cytosol secreted |
| Swiss Prot | P07738 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. |