Anti-SETMAR Polyclonal Antibody
品牌:solarbio | 货号:K004757P
英文名称 |
Anti-SETMAR Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
METNASE;Mar1 |
应用 |
WB IF |
稀释比例 |
WB 1:500-2000. IF 1:20-50. |
交叉反应 |
Human |
蛋白分子量 |
78kDa |
Gene ID |
6419 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human SETMAR |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human SETMAR |
Subcellular Locations |
Chromosome Nucleus |
Swiss Prot |
Q53H47 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. |