Anti-SETMAR Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-SETMAR Polyclonal Antibody

品牌:solarbio | 货号:K004757P

英文名称 Anti-SETMAR Polyclonal Antibody
宿主 Rabbit
别名 METNASE;Mar1
应用 WB IF
稀释比例 WB 1:500-2000. IF 1:20-50.
交叉反应 Human
蛋白分子量 78kDa
Gene ID 6419
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human SETMAR
性状 液体
Public Immunogen Range Recombinant protein of human SETMAR
Subcellular Locations Chromosome Nucleus
Swiss Prot Q53H47
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.