Anti-LRP5 Polyclonal Antibody
品牌：solarbio | 货号：K106841P
| 英文名称 | Anti-LRP5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BMND1;EVR1;EVR4;HBM;LR3;LRP-5;LRP7;OPPG;OPS;OPTA1;VBCH2;LDL receptor related protein 5 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 179kDa |
| Gene ID | 4041 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human LRP5 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human LRP5 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | O75197 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. |