Anti-Claudin 8 Polyclonal Antibody
品牌：solarbio | 货号：K106884P
| 英文名称 | Anti-Claudin 8 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CLDN8;HEL-S-79 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 25kDa |
| Gene ID | 9073 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human Claudin 8 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human Claudin 8 |
| Subcellular Locations | Cell membrane Cytoplasm |
| Swiss Prot | P56748 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma. |