Anti-IDH2 Polyclonal Antibody
品牌：solarbio | 货号：K007072P
| 英文名称 | Anti-IDH2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | IDH;IDP;IDHM;IDPM;ICD-M;D2HGA2;mNADP-IDH |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:100-300. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 51kDa |
| Gene ID | 3418 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human IDH2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human IDH2 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P48735 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. |