Anti-IDH2 Polyclonal Antibody
品牌:solarbio | 货号:K007072P
英文名称 |
Anti-IDH2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
IDH;IDP;IDHM;IDPM;ICD-M;D2HGA2;mNADP-IDH |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:100-300. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
51kDa |
Gene ID |
3418 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human IDH2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human IDH2 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P48735 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. |