Anti-NFATC1 Polyclonal Antibody
品牌：solarbio | 货号：K008199P
| 英文名称 | Anti-NFATC1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NFAT2;NFATc;NF-ATC |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 101/78/89/39kDa |
| Gene ID | 4772 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NFATC1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NFATC1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | O95644 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. |