Anti-AMACR Polyclonal Antibody
品牌：solarbio | 货号：K006663P
| 英文名称 | Anti-AMACR Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | RM;RACE;CBAS4;AMACRD |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:25-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 42kDa |
| Gene ID | 23600 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human AMACR |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human AMACR |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q9UHK6 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. |