Anti-CTNNA1 Polyclonal Antibody
品牌：solarbio | 货号：K006689P
| 英文名称 | Anti-CTNNA1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CAP102 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 100kDa |
| Gene ID | 1495 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CTNNA1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CTNNA1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P35221 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Catenin alpha-1?is a?protein?that in humans is encoded by the?CTNNA1?gene. Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. |