Anti-PHF19 Polyclonal Antibody
品牌：solarbio | 货号：K006366P
| 英文名称 | Anti-PHF19 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MTF2L1;PCL3;TDRD19B |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 66kDa |
| Gene ID | 26147 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PHF19 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PHF19 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q5T6S3 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Polycomb group (PcG) that specifically binds histone H3 trimethylated at ‘Lys-36′(H3K36me3) and recruits the PRC2 complex. Probably involved in the transition from an active state to a repressed state in embryonic stem cells: acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting H3K36me3 histone demethylases RIOX1 or KDM2B, leading to demethylation of H3K36 and recruitment of the PRC2 complex that mediates H3K27me3 methylation, followed by de novo silencing. |