Anti-VPS33B Polyclonal Antibody
品牌：solarbio | 货号：K005968P
| 英文名称 | Anti-VPS33B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | VPS33B |
| 应用 | WB IF |
| 稀释比例 | WB 1:1000-2000. IF 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 71kDa |
| Gene ID | 26276 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human VPS33B |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human VPS33B |
| Subcellular Locations | Cytoplasmic side Cytoplasmic vesicle Early endosome Late endosome membrane Lysosome membrane Peripheral membrane protein Recycling endosome clathrin-coated vesicle |
| Swiss Prot | Q9H267 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants. |