Anti-VGLL1 Polyclonal Antibody
品牌：solarbio | 货号：K007353P
| 英文名称 | Anti-VGLL1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | TDU;VGL1 |
| 应用 | WB |
| 稀释比例 | WB 1:2000-10000. |
| 交叉反应 | Human |
| 蛋白分子量 | 29kDa |
| Gene ID | 51442 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human VGLL1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human VGLL1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q99990 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. TDU interacted directly with the TEA domain family member, TEF1, and deletion of the Vg homology region abolished the interaction. The TDU-TEF1 dimer activated a reporter plasmid, and expression of TDU in Drosophila rescued loss of Vg function. The interaction was stronger in cardiac myocytes, suggesting a myocyte-specific factor may participate in the interaction. Vgll1 was weakly active in driving expression of a reporter gene from the mouse skeletal muscle alpha-actin promoter, and Vgll1 could partially reverse the inhibitory effect of TEF1 in this assay. |