Anti-VGLL1 Polyclonal Antibody
品牌:solarbio | 货号:K007353P
英文名称 |
Anti-VGLL1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
TDU;VGL1 |
应用 |
WB |
稀释比例 |
WB 1:2000-10000. |
交叉反应 |
Human |
蛋白分子量 |
29kDa |
Gene ID |
51442 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human VGLL1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human VGLL1 |
Subcellular Locations |
Nucleus |
Swiss Prot |
Q99990 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. TDU interacted directly with the TEA domain family member, TEF1, and deletion of the Vg homology region abolished the interaction. The TDU-TEF1 dimer activated a reporter plasmid, and expression of TDU in Drosophila rescued loss of Vg function. The interaction was stronger in cardiac myocytes, suggesting a myocyte-specific factor may participate in the interaction. Vgll1 was weakly active in driving expression of a reporter gene from the mouse skeletal muscle alpha-actin promoter, and Vgll1 could partially reverse the inhibitory effect of TEF1 in this assay. |