Anti-MID1 Polyclonal Antibody
品牌：solarbio | 货号：K005144P
| 英文名称 | Anti-MID1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BBBG1;FXY;GBBB1;MIDIN;OGS1;OS;OSX;RNF59;TRIM18;XPRF;ZNFXY |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 75kDa |
| Gene ID | 4281 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MID1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MID1 |
| Subcellular Locations | Cytoplasm cytoskeleton spindle |
| Swiss Prot | O15344 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the ‘RING-B box-coiled coil’ (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities. |