Anti-COX6A1 Polyclonal Antibody
品牌：solarbio | 货号：K003703P
| 英文名称 | Anti-COX6A1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CMTRID;COX6A;COX6AL |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-2000. IHC 1:20-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 12kDa |
| Gene ID | 1337 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human COX6A1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human COX6A1 |
| Subcellular Locations | Mitochondrion inner membrane |
| Swiss Prot | P12074 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented. |