Anti-GAD1 Polyclonal Antibody
品牌：solarbio | 货号：K003534P
| 英文名称 | Anti-GAD1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CPSQ1;GAD;SCP |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 67kDa |
| Gene ID | 2571 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human GAD1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human GAD1 |
| Subcellular Locations | Plasma Membrane |
| Swiss Prot | Q99259 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. |