Anti-IRF3 Polyclonal Antibody
品牌:solarbio | 货号:K008174P
英文名称 |
Anti-IRF3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
Interferon regulatory factor 3 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:25-100. |
交叉反应 |
Human |
蛋白分子量 |
47kDa |
Gene ID |
3661 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human IRF3 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human IRF3 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q14653 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |