Anti-MMP7 Polyclonal Antibody
品牌:solarbio | 货号:K006648P
英文名称 |
Anti-MMP7 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
MMP-7;MPSL1;PUMP-1 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human |
蛋白分子量 |
30kDa |
Gene ID |
4316 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human MMP7 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human MMP7 |
Subcellular Locations |
Secreted |
Swiss Prot |
P09237 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. |