Anti-RGR Polyclonal Antibody
品牌：solarbio | 货号：K005559P
| 英文名称 | Anti-RGR Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | RP44 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Rat |
| 蛋白分子量 | 32kDa |
| Gene ID | 5995 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RGR |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RGR |
| Subcellular Locations | Membrane Multi-pass membrane protein |
| Swiss Prot | P47804 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms. |