Anti-KCND2 Polyclonal Antibody
品牌：solarbio | 货号：K004366P
| 英文名称 | Anti-KCND2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | KV4.2;RK5 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Rat |
| 蛋白分子量 | 71kDa |
| Gene ID | 3751 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human KCND2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human KCND2 |
| Subcellular Locations | Cell junction Cell membrane Cell projection Multi-pass membrane protein Perikaryon dendrite dendritic spine postsynaptic cell membrane synapse |
| Swiss Prot | Q9NZV8 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes – shaker, shaw, shab, and shal – have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels. |