Anti-CHMP1B Polyclonal Antibody
品牌:solarbio | 货号:K005722P
| 英文名称 | Anti-CHMP1B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | C10orf2;C18-ORF2;C18orf2;CHMP1.5;Vps46-2;Vps46B;hVps46-2 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 22kDa |
| Gene ID | 57132 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CHMP1B |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CHMP1B |
| Subcellular Locations | Cytoplasm Endosome Late endosome membrane Peripheral membrane protein cytosol |
| Swiss Prot | Q7LBR1 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]). |