Anti-GMNN Polyclonal Antibody
品牌：solarbio | 货号：K003907P
| 英文名称 | Anti-GMNN Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Gem;MGORS6 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 24kDa |
| Gene ID | 51053 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human GMNN |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human GMNN |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | O75496 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. |