Anti-SMAD5 Polyclonal Antibody
品牌：solarbio | 货号：K006650P
| 英文名称 | Anti-SMAD5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DWFC;JV5-1;MADH5 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 52kDa |
| Gene ID | 4090 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SMAD5 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SMAD5 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q99717 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by BMP type 1 receptor kinase. Three transcript variants encoding the same protein have been found for this gene.?Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). May form trimers with the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit and SMURF1. Interacts with SUV39H1 and SUV39H2. Interacts (via MH2 domain) with LEMD3. Interacts with WWP1. |