Anti-CIDEA Polyclonal Antibody
品牌：solarbio | 货号：K005373P
| 英文名称 | Anti-CIDEA Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CIDE-A |
| 应用 | IF |
| 稀释比例 | IF 1:50-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 25kDa |
| Gene ID | 1149 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CIDEA |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CIDEA |
| Subcellular Locations | Lipid droplet Nucleus |
| Swiss Prot | O60543 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. |