Anti-MSH4 Polyclonal Antibody
品牌：solarbio | 货号：K008191P
| 英文名称 | Anti-MSH4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | hMSH4;MutS protein homolog 4 |
| 应用 | IHC |
| 稀释比例 | IHC 1:100-300. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 105kDa |
| Gene ID | 4438 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MSH4 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MSH4 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | O15457 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair. |