Anti-ICOS Polyclonal Antibody
品牌：solarbio | 货号：K006766P
| 英文名称 | Anti-ICOS Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AILIM;CD278;CVID1 |
| 应用 | IHC |
| 稀释比例 | IHC 1:20-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 23kDa |
| Gene ID | 29851 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ICOS |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ICOS |
| Subcellular Locations | Cell membrane Cytoplasm |
| Swiss Prot | Q9Y6W8 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.?Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes. |