Anti-ANGPTL4 Polyclonal Antibody
品牌：solarbio | 货号：K006664P
| 英文名称 | Anti-ANGPTL4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NL2;ARP4;FIAF;PGAR;HFARP;pp1158;ANGPTL2 |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 45kDa |
| Gene ID | 51129 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ANGPTL4 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ANGPTL4 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q9BY76 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. |