Anti-AGO1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-AGO1 Polyclonal Antibody

品牌:solarbio | 货号:K004319P

英文名称 Anti-AGO1 Polyclonal Antibody
宿主 Rabbit
别名 EIF2C;EIF2C1;GERP95;Q99;hAgo1
应用 WB
稀释比例 WB 1:500-1000.
交叉反应 Human Mouse
蛋白分子量 97kDa
Gene ID 26523
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human AGO1
性状 液体
Public Immunogen Range Recombinant protein of human AGO1
Subcellular Locations Cytoplasm P-body
Swiss Prot Q9UL18
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.