Anti-HTR2B Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-HTR2B Polyclonal Antibody

品牌:solarbio | 货号:K004123P

英文名称 Anti-HTR2B Polyclonal Antibody
宿主 Rabbit
别名 5-HT(2B);5-HT-2B;5-HT2B
稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:10-100.
交叉反应 Human Mouse Rat
蛋白分子量 54kDa
Gene ID 3357
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human HTR2B
性状 液体
Public Immunogen Range Recombinant protein of human HTR2B
Subcellular Locations Cell junction Cell membrane Multi-pass membrane protein synapse synaptosome
Swiss Prot P41595
克隆类型 Polyclonal Antibody
背景资料 This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene.