Anti-QDPR Polyclonal Antibody
品牌:solarbio | 货号:K004170P
英文名称 |
Anti-QDPR Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
DHPR;PKU2;SDR33C1 |
应用 |
WB IF |
稀释比例 |
WB 1:500-2000. IF 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
26kDa |
Gene ID |
5860 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human QDPR |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human QDPR |
Subcellular Locations |
Cytosol secreted |
Swiss Prot |
P09417 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. |