Anti-LIFR Polyclonal Antibody
品牌:solarbio | 货号:K106613P
英文名称 |
Anti-LIFR Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CD118;LIF-R;SJS2;STWS;SWS |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human |
蛋白分子量 |
115kDa |
Gene ID |
3977 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human LIFR |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human LIFR |
Subcellular Locations |
Cytoplasm Cell membrane |
Swiss Prot |
P42702 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. |