Anti-IL18BP Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-IL18BP Polyclonal Antibody

品牌:solarbio | 货号:K004534P

英文名称 Anti-IL18BP Polyclonal Antibody
宿主 Rabbit
别名 IL18BPa
稀释比例 WB 1:500-2000. IHC 1:50-100. IF 1:50-100.
交叉反应 Human Mouse
蛋白分子量 21kDa
Gene ID 10068
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human IL18BP
性状 液体
Public Immunogen Range Recombinant protein of human IL18BP
Subcellular Locations Secreted
Swiss Prot O95998
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn’s disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.