Anti-CRH Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CRH Polyclonal Antibody

品牌:solarbio | 货号:K007404P

英文名称 Anti-CRH Polyclonal Antibody
宿主 Rabbit
别名 CRF
稀释比例 WB 1:200-1000. IHC 1:25-100.
交叉反应 Human Mouse Rat
蛋白分子量 21kDa
Gene ID 1392
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CRH
性状 液体
Public Immunogen Range A synthetic peptide of human CRH
Subcellular Locations Cytoplasm Nucleus
Swiss Prot P06850
克隆类型 Polyclonal Antibody
背景资料 Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery.