Anti-GMNN Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-GMNN Polyclonal Antibody

品牌:solarbio | 货号:K003907P

英文名称 Anti-GMNN Polyclonal Antibody
宿主 Rabbit
别名 Gem;MGORS6
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human
蛋白分子量 24kDa
Gene ID 51053
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human GMNN
性状 液体
Public Immunogen Range Recombinant protein of human GMNN
Subcellular Locations Cytoplasm Nucleus
Swiss Prot O75496
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.

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