Anti-RPS27 Polyclonal Antibody
品牌：solarbio | 货号：K004748P
| 英文名称 | Anti-RPS27 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MPS-1;MPS1;S27 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 9kDa |
| Gene ID | 6232 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RPS27 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RPS27 |
| Subcellular Locations | Cytosol Nucleus |
| Swiss Prot | P42677 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S27e family of ribosomal proteins and component of the 40S subunit. The encoded protein contains a C4-type zinc finger domain that can bind to zinc and may bind to nucleic acid. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. Mutations in this gene have been identified in numerous melanoma patients and in at least one patient with Diamond-Blackfan anemia (DBA). Elevated expression of this gene has been observed in various human cancers. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. |